Biologics for Psoriasis

What are Biologics for Psoriasis?

Biologics designed for psoriasis treatment are advanced medications tailored to treat moderate to severe plaque psoriasis and its related condition, psoriatic arthritis. They specifically target certain immune system components which contribute to psoriasis. Presently, there are four main classes of biologics:

  • TNF-alpha inhibitors: Notable examples include Humira, Enbrel, and Cimzia.

  • IL-17 inhibitors: Such as Taltz, Cosentyx, and Siliq

  • IL-23 inhibitors: Including Skyrizi, Tremfya, and Ilumya

  • IL-12/IL-23 inhibitors: Like Stelara

The decision on which biologic to use is influenced by various factors, such as:

  • Concurrent medical conditions

  • Affected psoriasis areas

  • Presence of psoriatic arthritis

Typically, these medications are considered for patients who haven't achieved satisfactory results with topical treatments.

How do Biologics for Psoriasis Work?

Biologics operate by targeting specific proteins and immune cells responsible for causing inflammation, a primary symptom of psoriasis. By reducing this inflammation, biologics can decrease the number and severity of plaques, relieve pain and itching, and improve other symptoms.

What are Possible Side Effects of Biologics for Psoriasis?

Before commencing treatment, patients generally need a blood test to screen for potential infections. Periodic checks may be required throughout the treatment course. The likelihood of infections can vary based on the specific biologic. Should symptoms of an infection arise, patients may be advised to delay their injection, allowing the immune system to combat the infection. Common side effects comprise:

  • Injection site reactions

  • Potential rare complications, which your healthcare provider can provide detailed insights on during the prescription phase.

How are Biologics for Psoriasis Used?

Administered via injection, the frequency of biologics varies based on the specific drug, ranging from bi-weekly to every twelve weeks. Detailed instructions on self-administration are typically provided upon prescription. It's pivotal to note:

  • These medications necessitate refrigeration.

  • They should be taken out approximately 30 minutes prior to injection for optimal use.

While effective in symptom management, these biologics don't cure psoriasis. If the treatment is discontinued, symptoms might return within a period ranging from weeks to months. Moreover, special insurance approval may be necessary for acquiring these medications.

THIS CONTENT IS INTENDED SOLELY FOR EDUCATIONAL PURPOSES AND MAY NOT BE COMPREHENSIVE. IT DOES NOT CONSTITUTE MEDICAL ADVICE. PLEASE REFER TO OUR TERMS OF USE FOR FURTHER DETAILS. ALWAYS CONSULT WITH YOUR HEALTHCARE PROVIDER BEFORE MAKING ANY MEDICAL DECISIONS.