Topical Vitamin D Analogs

What are topical vitamin D analogs?

Topical vitamin D analogs, such as calcipotriene (Dovonex) and calcitriol (Vectical), have become staple treatments for psoriasis management. Mimicking the effects of vitamin D in the skin, they help slow down the rapid growth of skin cells, reducing scaling and thickening of psoriasis plaques. Additionally, they have anti-inflammatory properties that soothe redness and irritation.

What are possible side effects of topical vitamin D analogs?

While many patients tolerate these treatments well, some might experience skin irritation, itching, burning, and redness. Rarely, especially if used excessively, they can lead to elevated calcium levels in the urine or blood. This is why it's essential to use the medication as prescribed and regularly monitor with a dermatologist.

How are topical vitamin D analogs used?

Applied directly to psoriasis plaques, these treatments are typically used once or twice daily, depending on the specific product and dermatologist's advice. Combining them with other treatments, like topical steroids, can sometimes enhance effectiveness and reduce side effects.