Cyclosporine

What is Cyclosporine?

Cyclosporine is a potent immunosuppressive drug utilized for several severe dermatological conditions like eczema and psoriasis that have proven resistant to other treatments. It becomes a consideration especially when strong medications, including oral steroids, do not sufficiently manage the condition. Originally, cyclosporine's primary use was as an organ transplant medication. The drug is typically prescribed for short durations, usually spanning weeks to months, to get the condition under control.

How does Cyclosporine work?

  • Immunosuppression: Cyclosporine suppresses the immune response, thereby reducing inflammation and other symptoms in dermatological conditions.

  • Targeting T-cells: The medication mainly inhibits the activation and proliferation of T-cells, which play a significant role in immune reactions.

What are possible side effects of Cyclosporine?

Cyclosporine can bring about a variety of side effects, which is one of the reasons for its restricted usage. Its potential interactions with numerous other medications may also necessitate alterations in an individual's current medication regimen. Potential side effects encompass:

  • Elevated blood pressure

  • Kidney impairment

  • Excessive hair growth

  • Nausea or vomiting

  • Enhanced vulnerability to infections due to immune system suppression

Note: Regular lab tests are vital to track the medication's effects on the liver, kidneys, and electrolyte levels.

How is Cyclosporine used?

  • Administration: Cyclosporine is taken orally.

  • Dosage: The dosage is determined based on the individual's weight, so obtaining an accurate weight measurement is pivotal.

  • Interactions: Given its multiple interactions with other drugs, it's crucial to maintain an up-to-date list of all medications taken.

  • Frequency: The drug should be ingested multiple times a day.

  • Monitoring: Regularly checking blood pressure during treatment is essential.

  • Avoidance: Grapefruit juice must not be consumed while on cyclosporine.

Precautions:

  • Always take Cyclosporine as prescribed by a healthcare provider.

  • Consistently monitor for side effects and promptly report any unusual symptoms.

  • Given the drug's immune-suppressing properties, take extra precautions to prevent infections.

  • Regular blood tests are needed to ensure the drug's safety and efficacy.

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