Vismodegib (Erivedge)

What is vismodegib?

Vismodegib (Erivedge) is an oral chemotherapy medication specifically designed to treat individuals with metastatic basal cell carcinoma, multiple basal cell carcinomas, or inoperable basal cell carcinoma. The drug acts by inhibiting the growth of basal cell carcinomas. It can be administered as a standalone treatment or used to reduce the size of the carcinoma before surgical removal.

What are possible side effects of vismodegib?

Vismodegib does not necessitate bloodwork monitoring and does not suppress the immune system. However, it can have several side effects that may impact your quality of life, such as loss of taste, weight loss, hair loss, and muscle cramps. While these side effects are generally mild to moderate, they can become severe. If you experience severe side effects, consult your healthcare provider for recommendations to manage them.

How is vismodegib used?

Vismodegib is administered once daily and is typically prescribed for a duration of 12-18 months, or until the basal cell carcinoma is no longer detectable through biopsy. Alternatively, the medication may be used until the carcinoma has shrunk sufficiently for surgical removal to be viable. If side effects become troublesome, it's possible to take intermittent breaks from the medication, such as taking it from Monday to Friday and pausing over the weekend.

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