Basal Cell Carcinoma

What is basal cell carcinoma?

Basal cell carcinoma (BCC) is the most prevalent type of skin cancer. It arises when mutations occur in the basal cells of the skin, which are responsible for producing new skin cells. BCC predominantly affects individuals with fair skin and those who have had substantial sun exposure. Although it is infrequently fatal, untreated BCC can spread across the skin, leading to disfigurement. Prompt treatment is essential.

What causes basal cell carcinoma?

BCC develops when mutations accumulate in the basal cells of the epidermis. The primary culprit behind these mutations is UV radiation from the sun or tanning beds. Additionally, individuals with a family history of BCC or those on immunosuppressive medications are at an elevated risk. Over time, accumulated mutations can lead to uncontrolled cellular proliferation, resulting in tumor formation. The risk of BCC increases with age, and it is most common in individuals over the age of 50.

What are the symptoms of basal cell carcinoma?

The appearance of BCC can vary, with symptoms including:

• A smooth, waxy bump that may be pink, white, or flesh-colored

• A lesion that bleeds easily

• A scar-like lesion that's brown in color

• A flat, crusted lesion

• A firm, red or pink growth

How do I treat basal cell carcinoma?

Treatment strategies for BCC depend on factors such as location, depth, and size of the carcinoma. Typically, surgical excision under local anesthesia in a clinical setting is the primary approach. Other treatment options include:

• Mohs Micrographic Surgery: This technique involves sequential removal of skin layers, particularly in high-risk or cosmetically sensitive areas.

• Oral Medications: Such as vismodegib (Erivedge), which might be considered for difficult-to-excise areas or when multiple lesions are present.

• Topical Medications: Imiquimod or 5-fluorouracil (5-FU) are used primarily for superficial lesions.

• Electrodesiccation and Curettage: This method involves scraping away the lesion and using an electric needle to treat the area.

• Cryotherapy: Freezing is generally reserved for smaller or superficial lesions.

How do I prevent basal cell carcinoma?

The majority of BCC cases can be prevented by minimizing exposure to sunlight and avoiding tanning beds. Using sunscreens with an SPF of 30 or higher, wearing hats, and using protective clothing are crucial preventive measures. Regularly monitoring the skin for new or evolving lesions ensures early detection and timely treatment.